Doctor’s day is celebrated in the west on march 30- the day when Dr Crawford W. Long, became the first physician to use ether anesthesia in surgery
Wednesday, July 1, 2009
Happy Doctor's Day
Doctor’s day is celebrated in the west on march 30- the day when Dr Crawford W. Long, became the first physician to use ether anesthesia in surgery
Thursday, June 25, 2009
Influence of vitamins in thyroid related illness
Patients with thyroid disease should take supplements containing molecules with anti-oxidant properties, such as vitamin C, vitamin E, and coenzyme Q10. (Vitamin C and B-complex vitamins are very important.) Induction of B1 is supposed to be the best for helping thyroid to function properly in views of some doctors. B1 is mainly found in brewer’s yeast and germinated wheat. For non-vegetarians source of this vitamin is liver part of meat.
Patients suffering from thyroid diseases mostly suffer from the following symptoms and disorders, they should take the vitamins in the form of food products or even can take pills of the mentioned vitamins on the advice of a physician.
Vitamins recommended in thyroid related diseases and symptoms
A- Kidney stone
E-Menses
B1-Appetite, constipation, fatigue,
B1 and B2 –skin problems
B6-Emotional disturbance, gall bladder stone.
B6 and D-Anaemia, weakness
B12-Pernicious anemia
LINKS AND REFERENCES
Vitamin D deficiency and thyroid diseases
Tuesday, June 16, 2009
Remedial measures for Monsoon ailments
General and specific management for the most common monsoon related diseases.
Cholera
Patient must be kept at rest as warm as possible,no solid food whatever should be given, water may be given as desired.Milk is the best food if it is tolerated.(according to J..H Clark ‘The Prescriber’)
Homoeopathic management: Ver alb, Camphor, Jatropha, cupmet, ars, podo, elaterium, arg nit
Influenza
Rest in bed, warmth,plenty of fluid intake, support with nourishment in a digestible form, as long as the symptoms are acute. There is a modified form of the disease, which requires care, but not necessarily either rest in bed or confinement to the house.
Homoeopathic management: ars alb, baptisia, Influenzinum, eupatorium p, gelsemium, bryonia, rhus tox
Post influenzal cough- sangunaria, sticta
Jaundice
The patient must fed on the lightest diet barley water, thin gruel, skim-milk. If there is much itching, sponging with vinegar and hot water (one pint in six) is agreeable.
Homoeopathic management: merc sol, bryonia, china, hepar sulph, chamomilla.
Dysentery
When dysentery appears make sure that water is good.If not use boiled and filtered water to drink.House must be carefully disinfected.Unripe fruit must be avoided.the diet must be confined to gruel and farinaceous food with as much as cold water as patient likes.
Homoeopathic management:merc cor, colocynth, ipecac, aloes,
Asthma
General management :Try to avoid all triggering factors like dust,pollen,animal danders etc.Practise Breathing exercises.
Homoeopathic management:nat sulph, dulcamera, kali carb, aur, china, ipecac
Rheumatic/rheumatoid complaints
Gen management: Patient should be advised to wear woolen clothes since the woolen garments retain the heat and let the perspiration escape. Presence of lactic acid in the system gives rise to most of the symptoms. So modify the dietary pattern according to that.Grain foods are the best choice. (Oats, barely, wheat etc)
Dietery restrictions include meat, take milk but sparingly, avoid sweets ,watery fruits and vegetables. Grain foods are the best choice.(oats,barely,wheat etc)
Homoeopathic management:Rhus tox, bryonia, colchicum, dulcamara, kalmia, Calc phos, kali bich.
Links and references
The prescriber-JH CLARK
Hompath /therapeutics
Administation of camphor in cholera from the book'Cure and Prevention of the Asiatic Cholera - (1831)'
Friday, June 12, 2009
Swine flu formally declared as pandemic by WHO
Swine flu- Our earlier post
Links
http://news.yahoo.com/s/ap/20090611/ap_on_he_me/un_un_swine_flu
http://www.who.int/csr/disease/swineflu/en/
Thursday, June 11, 2009
cell phone elbow
How it happens?
Health experts say that those who are holding the phone near the ear for a prolonged period are at a risk of developing painful condition of arm. By bending their elbow too tightly and for too long could damage the ulnar nerve.
Dr. Benson, a professor of orthopedic surgery at Northwestern University School of Medicine, explains” The more you bend it, for example when using a phone, the more it stretches. It diminishes the blood supply, and the blood is not flowing through the nerves.”
Symptoms
Sufferers can present with numbness and tingling from the elbow to the fingers. More than that they find it difficult to perform their day to day activities.In order to resolve this condition up to some extent, experts suggest mobile users to switch the handset from hand to hand so often.
Tuesday, June 9, 2009
Are pictorial warnings against tobacco effective?
India made it mandatory to put pictorial warning on all tobacco products from may 31.
Advantages of pictorial warnings
They attract the attention of common man and make it difficult to ignore the harmful effects of tobacco. Smokers knew more about the health effects from smoking as a result of pictorial warning.
Links
http://www.tobaccoplusindia.com/book.php?p_id=40
http://ibnlive.in.com/news/pictorial-warning-on-tobacco-products-from-today/93814-17.html
Monday, June 8, 2009
Utility chart for the probable diagnosis of thyroid disorders
Friday, June 5, 2009
M.D.entrance coaching programme
classes conducted in three centers all over kerala-thiruvananthapuram , kollam , kozhikode
- eminent faculty- all are post graduates or lecturers in various homoeopathic colleges in kerala
- well prepared study materials
- all together 14 classes( sundays) and two model exams
- very high success raste in previous years
trivandrum - IVA Hall, dharmalayam road, tvm 1 - May 24
kollam - Govt PWD Rest house, chinnakada, kollam - May 31
kozhikode - Pullians arcade, behind MCC bank, Calicut 1 - May 17
for further detalis contact
Dr.Abhilash.M - 9446072887
Dr Nidhin dev.S - 9446541238
Tribute to DR.J.T KENT ON HIS DEATH ANNIVERSARY
- "True some men do some good work without the repertory, but they also do poor work, more than they would do with it"- Dr.Kent .J.T
- "The mechanical use of the repertory never leads to artistic prescribing nor to remarkable results" - Dr.Kent .J.T
- Which is the best repertory ?
The best is that which one makes oneself _ Dr.Kent .J.T
Thursday, June 4, 2009
JUNE 5 WORLD ENVIRONMENT DAY - WED
World Environment Day (WED) was established by the UN General Assembly in 1972 to mark the opening of the Stockholm Conference on the Human Environment.
Commemorated yearly on 5 June, WED is one of the principal vehicles through which the United Nations stimulates worldwide awareness of the environment and enhances political attention and action. The day's agenda is to:
The theme for WED 2009 is 'Your Planet Needs You-UNite to Combat Climate Change'. It reflects the urgency for nations to agree on a new deal at the crucial climate convention meeting in Copenhagen some 180 days later in the year, and the links with overcoming poverty and improved management of forests.
This year’s host is Mexico which reflects the growing role of the Latin American country in the fight against climate change, including its growing participation in the carbon markets.
Mexico is also a leading partner in UNEP's Billion Tree Campaign. The country, with the support of its President and people, has spearheaded the pledging and planting of some 25 per cent of the trees under the campaign. Accounting for around 1.5 per cent of global greenhouse gas emissions, the country is demonstrating its commitment to climate change on several fronts.
Mexican President Felipe Calderon states that the WED celebration will “further underline Mexico's determination to manage natural resources and deal with the most demanding challenge of the 21st century – climate change.”
People around the world will unite for the planet on 5 June for World Environment Day 2009, with a strong call for environmental action just six months before the crucial United Nations climate change talks in Copenhagen.
This year's theme is 'Your Planet needs You! Unite to combat climate change' - a topic that reflects everyone's individual responsibility to protect the planet, as well as the urgency for nations to agree on a new climate change deal in December.
World Environment Day is truly a People's Day: it is the chance for everyone, young and old, with their community or with close friends, to show that they care for the planet.
This year's host is Mexico, reflecting the country's growing role in the fight against climate change - with its increasingly strong participation in global carbon markets, its massive tree planting campaigns and its natural resource management.
United Nations Secretary-General Ban Ki-moon said: "On this World Environment Day. I encourage all people to take concrete steps toward making the planet greener and cleaner. Switch off the lights. Take public transportation. Recycle. Plant a tree. Clean up your local park. Hold corporations responsible for their environmental practices. And urge your government representatives to Seal the Deal in Copenhagen."
Achim Steiner, UN Under-Secretary-General and Executive Director of the United Nations Environment Programme, said: "I am delighted that Mexico and its people will be the 2009 global hosts of the annual United Nations celebrations on 5 June under the theme 'Your Planet Needs You! Unite to Combat Climate Change'. Mexico is among a group of nations showing real leadership on the challenges of our age - from climate change to bringing environmental goods and services into the mainstream of national and international economics."
World Environment Day is a truly global event, and as such it will be celebrated on every continent - from remote villages to sprawling capitals. Here are some of the highlights of this year's celebration.
Monday, May 25, 2009
Utility of barium swallow and barium meal in various abdominal conditions.
Utility
Links
barium swallow and barium meal tests
Barium swallow image
Friday, May 22, 2009
Health Benefits of insoluble and soluble dietary fibers.
Fibers may be classified as insoluble and soluble fiber.
Insoluble fiber includes the woody or structural parts of plant such as fruits and vegetables and bran coating around the wheat. This kind of fiber is responsible in alleviating irregular bowel movement and constipation. It helps to protect against colon cancer.
How it acts?
Insoluble fiber pass through the GI tract largely unchanged and speeds up the passage of materials through the tract.
Soluble fiber found in abundance in beans, oats, barely, broccoli, apples, prunes and citrus fruits. It has the consistency of gel and tends to slow the passage of materials through the tract. It is responsible for easy elimination of your bowel and it is also a great help in reducing your cholesterol and blood sugar levels.
How it acts?
-One possible explanation for the relationship of soluble fiber to cholesterol level is that the fiber binds bile salts (cholesterol is a precursor to bile salt formation) and prevents their reabsorption.
-Fiber, particularly soluble fiber, can slow down the absorption of sugar, which for people with diabetes, can help to improve blood sugar levels. A high-fiber diet may also reduce the risk of developing type 2 diabetes.
Links
how fiber protects you from various disease conditions
All about dietary fiber
Tuesday, May 19, 2009
Interesting human body statistics
Heart –The hollow muscle pumps enough blood in an average lifetime to fill the fuel tanks of 56 moon rockets. Its involuntary contractions begin 4 weeks after conception, before nerve cells are formed and continue to pulse even out of the body in saline solution. Muscle cells of the heart generate a total electric current of about 2 watts that commands the fibers to contract.
Lungs-Adult human lung have an internal area of 93 m2, which is 40 times the external surface of human body.
Stomach –It produces 2 litres of hydrochloric acid daily.5 lakhs cells of stomach’s inner walls are replaced every minute so that the acid doesn’t damage the walls.
Muscles-There are 639 muscles, which account for 40% of the total body weight. It takes 17 muscles to smile and 42 to stare.
Tongue-The tongue contains more than 10,000 taste buds, which are renewed weekly. It can distinguish 500 different tastes.
Eyes-We spends 30 minutes everyday, being blind. (The time taken for blinking)
Ear- Our ear can detect 1500 different tunes and 350db of loudness.
Sunday, May 17, 2009
Various approaches to kidney stone diet
- Doctors used to prescribe a low calcium diet for preventing kidney stones. Changing the amount of calcium in the diet causes very little change in the blood level of calcium. Blood calcium level kept steady by balancing the absorption of calcium from diet and taking calcium from bones when it is needed. The kidney filters substances from the blood; so changing the dietary intake of calcium does not change the amount of calcium that is filtered by the kidneys.
- Citric acid can protect against kidney stone formation. Citric acid in its natural form, such as from citrus fruits, citric acid does not alkalinize the urine as citrate does. It prevents small stones from becoming “problem stones” by coating them and preventing other material from attaching and building onto the stones. Moreover it inhibits stone formation and breaks up small stones that are beginning to form. It is for this reason, that citrus fruit, especially lemons should be plentiful on the kidney stone diet. The exception to this rule is grapefruit juice.
- Another approach to prevent kidney stones in adults is to eat calcium rich foods and avoid foods rich in oxalates. Calcium and oxalate always have a tendency to bind in the intestine). If oxalate rich foods (Chocolate Tea Spinach Beet tops Peanuts Almonds) are restricted in the diet, taht can bve solved and chances of formation of stones can be reduced.
- Insoluble fiber (found in wheat, rye, barley, and rice) that may help to reduce calcium in the urine. It combines with calcium in the intestines, so the calcium is excreted with the stool instead of through the kidneys. Moreover insoluble fiber also speeds up movement of substances through the intestine, so there will be less time for calcium to be absorbed.
- Potassium reduces urinary calcium excretion, which in turn lowers the risk of kidney stone formation. So foods rich in potassium should be included in the diet.
- Protein rich foods increase urinary calcium and should be reduced in the kidney stone diet.
- It is believed that sugar can increase urinary oxalate and urinary calcium.
kidney stone diet
http://www.medindia.net/patients/patientinfo/diet-kidney-stones.htm
Citric acid and kidney stones
Wednesday, May 13, 2009
Physical characteristics and abnormal constituents of urine part1
Odour: Foul smelling urine is a common symptom of urinary tract infection. Fruity odour is associated with diabetes mellitus, starvation, dehydration or ketone body formation. Patients with maple syrup urine diseases and phenyl ketonuria may present with distinctive odour of the urine.
Specific gravity: Low specific gravity (below 1.005) associated with diabetes insipidus, acute tubular necrosis, nephrogenic diabetes insipidus and pyelonephritis. High specific gravity (above 1.035) occurs in patients who are in shock or who suffer from nephritic syndrome, dehydration, and acute glomerulo nephritis.
PH: Ranges between 4.6 -8.0.High protein diets increase the acidity of urine; vegetarian diets increase the alkalinity. (Normal fresh urine is nearly always slightly acidic, except after a meal.) Value greater than 7 may be due to metabolic/ respiratory alkalosis, Fanconi’s syndrome. Ph value below 7 may be due to fever, phenyl ketonurea, alkaptonurea and acidosis.
Blood and tissue cells: Red blood cells in the urine can be due to vigorous exercise or exposure to toxic chemicals. High number of white blood cells in the urine is usually a symptom of urinary tract infection. Certain other causes of haematurea are bacterial infections, parasitic infections including malaria, obstructions in the urinary tract, scurvy, sub acute bacterial endocarditis, traumatic injuries, and tumors. A large number of cells from tissue lining can indicate damage to the small tubes that carry material into and out of the kidneys.(In females, one should make sure that the urine sample was not contaminated with menstrual blood from vagina.)
Casts: They are small fibrous objects that are formed when protein and other materials settle in the kidney tubules and collecting ducts. Large number of casts in urine specimen is a sign of kidney disease.
Sources
Hutchison’s clinical method
Davidson's Principles and practice of medicine
Haematurea
Monday, May 11, 2009
Medical inventions and Discoveries
Chemotherapy - Ehrlich (1909)
Pace maker - Zoll (1952)
Hearing aid - Sonotone Corporation, USA (1952).
Heart –lung machine - Dr. John H. Gibbon. (1953)
Artificial heart - Willem kolff (1957)
LASER - Gould (1957)
MRI -Damadian (1971)
Cloning DNA - Boyer, Cohen (1973)
CT Scan - Hounsfield (1973)
HIV -M.Cockerell. (1984)
Microscope
Compound - Z.Janssen (1590)
Electron -Ruska knoll (1931)
Thursday, May 7, 2009
Hepatitis markers and its usual significance
- HBsAg
- Anti-HBs (surface antibody)
- HBeAg*
- Anti-HBe*
(HBeAg usually represents that , there is an active viral replication. The disappearance of HBeAg and appearance of anti Hbe usually means that the level of viral replication and the associated liver disease has lessened.The individual is less capable of infecting others.)
- HBV-DNA
Active viral replication and on going liver disease,patient infectious.
- HBcAg
- Anti-HBc (core antibody)
Links
Approach to the management of incidentally detected HBsAg carrier
Monday, May 4, 2009
Concept of Polypill and the criticism
The pill is a result of a three-year study conducted by three doctors from St. John’s Medical College, Bangalore along with a team of experts from McMaster University, Hamilton, Canada.
The combination
The "polypill" would contain 3 blood pressure medications at low dose:
a diuretic, such as bendroflumethiazide,a beta-blocker such as atenolol,
an ACE inhibitor such as enalapril.
This is combined with
a statin such as simvastatin,aspirin at a dose of 75 mg and
Follic acid(Follic acid has been shown to reduce the level of homocysteine in the blood which is another risk factor for heart disease).
The criticism
Although several group of physicians accept the rational combination of proven life-saving drugs in easily administered and cost-saving formulations, especially for the secondary prevention of Cardio vascular diseases, they expresses their concern over, proclaiming polypill as the principal pathway to primary prevention of Cardio vascular disease.
Several scientific questions currently remain, especially with respect to primary prevention. How will this drug combination alter with behaviour change involving healthy diets, regular exercise, and smoking cessation?
Critics also worry that the promised protection of a polypill may work against people giving up unhealthy habits like smoking or bad diet.
Another criticism is that,a person would be subjected to different drugs unnecessarily even if he had one ailment.
Links
Can polypill replace poly-policy for heart health
Saturday, May 2, 2009
SWINE FLU
Further reading: Swine flu
Wednesday, April 29, 2009
Nail as a diagnostic tool PART 2
Leukonychia. These marks are common, nonuniform, white lines found in differing spots on one or more nails. It should not be confused with Mees line(due to arsenic poisoning)and Muehrcke's line which are parallel to the lanula across the entire nail bed and occur in more than one nail.
Beau's lines. This condition presents as a transverse depressions in the nail that result from trauma, exposure to cold, Raynaud's disease, or any episodic disease condition serious enough to disrupt the normal nail growth
Raynauds phenomenon can lead to thinning and longitudinal ridging of nail plate
Muehrcke's line demonstrates as a transverse white bands parallel to the lanula. These bands usually occur in pairs and extend all the way across the nail.
Half and half nail with a white proximal and red or brown distal half is occasionally seen in patient with chronic renal failure
Whitening of nail plates may be related to hypoalbuminaemia as in cirrhosis of the liver
Nail fold erythema is a useful physical sign in dermatomyositis, systemic sclerosis and SLE
References :
Huchisons clinical method
Davidson’s Principles and practice of medicine
Nail disorder index
PART 1
Sunday, April 26, 2009
Vaccine for Diabetes ???
READ DETAILS.....
http://www.nhs.uk/news/2009/03March/Pages/DiabetesVirusLink.aspx
Friday, April 24, 2009
Nail as a diagnostic tool PART 1
References :
Huchisons clinical method
Davidson’s Principles and practice of medicine
The journal of family practice- Nail disorders and systemic disease: What the nails tell us
Glossary of nail conditions
Thursday, April 23, 2009
Wednesday, April 22, 2009
Quick references to the clinical presentation of cranial nerve lesions.
Optic nerve:Visual field defects and loss of visual acuity may result from fractures in the orbit, lesion along the visual pathway and diseases of nervous system.
Oculomotor nerve:A lesion in the nerve causes strabismus ,ptosis of upper eyelid ,pupil dilatation,the movement of eye ball downward and outward on the damaged side,loss of accommodation for near vision and diplopia.
Trochlear nerve:In trochlear nerve paralysis,diplopia and strabismus occur.
Trigeminal nerve:Injury results in paralysis of muscles of mastication and loss of sensation of touch and temperature.Neuralgia of one or more branches of trigeminal nerve is called trigeminal neuralgia.(Tic douloureux)
Abducens nerve: With the damage to this nerve, the affected eyeball move laterally beyond the midpoint and the eye is usually directed medially.
Facial nerve:Injury produces paralysis of facial muscles called bell’s palsy,loss of taste and loss of ability to close the eyes even during sleep.
Vestibulocochlear nerve:Injury to the cochlear branch may cause tinnitus or deafness.Injury to the vestibular branch may cause vertigo,ataxia, and nystagmus.
Glossopharyngeal nerve:Injury results in difficulty during swallowing,reduced secretion of saliva,loss of sensation in the throat and loss of taste.
Vagus nerve:Damage to this nerve in the upper body interfere with swallowing,paralyses the vocal cords,and interrupts the sensation from many organs.
Acessory nerve:Damage to this nerve results in paralysis of sternocleido mastoid and trapezius muscle present with inability to raise the shoulder and turning the head.
Hypoglossal Nerve.Injury results in difficulty in chewing ,speaking and swallowing. The tongue when protruded turn towards the affected side and the affected side become atrophied,shrunken,and deeply furrowed.
Further reading
Cranial nerve examination
Sunday, April 19, 2009
LINKS for Medical professionals
http://www.shirleys-wellness-cafe.com/homeopathy-resources.htm
http://www.homoeopathy-course.com/appr-p-2.htm Illustrates Philosophy and Utility of Miasm,Miasmatic Diagnostic Classifications,Miasmatic Diagnosis of Clinical Classifications,Miasmatic Ancestral Tips,Miasmatic Repertory,Miasmatic Weightage of Medicines by Bengal allen institute
Similima,the largest portal on homoeopathy, designed by post graduate homoeopaths,it includes, latest information on homoeopathy,research articles ,study materials , and educational materials for exam preperation by Dr.Mansoor ali and team
hpathy- A Portal for Homeopathic Medicine, Homeopathy Remedies, Cures, Treatment, Books, Information about Software & Doctors
Modern homoeopathy-An evidence based Homoeopathy site includes Online Treatment, Articles, Cured Cases, Online Journal by Dr. Pawan S Chandak.
Homoeopathic forum by abchomoeopathy http://abchomeopathy.com/forums.php
Resources for all Medical professionals.......
Enjoy the animated graphics and extensive discussions of topics in
cardiology. http://www.heartpoint.com/gallery.html
gatrolab.net -featuring image library,endoscopic piture archieves,endoscopic learning center,links to gastrointestinal websites and much more…
http://www.gastrolab.net/index.htm
List of sites offering links to audible examples of normal and abnormal Breath Sounds on loop recordings that you may listen to on your computer.
http://medzoom.net/breathsounds.html
Flash video of cardiac cycle: http://library.med.utah.edu/kw/pharm/hyper_heart1.html
Dermatology atlas database: http://tray.dermatology.uiowa.edu/DermImag.htm
MARTINDALE'S The virtual medical centre
http://www.martindalecenter.com/MedicalClinical_Exams.html#EXAMS-ALL
X-Plain.net- includes interactive patient education programs that use illustrations and animations to simplify concepts, narration to read the text, and questions to verify understanding.
Updated monthly............
Friday, April 17, 2009
Cardiovascular fitness against Aerobic fitness
To achieve this, exercise 15-30 minutes/ four times a week without worrying about your heart rate(unlike aerobic fitness). Someone who exercises regularly may have a resting heart rate of 55 or 60 beats per minute. A person who does no regular exercise may have a resting rate of 70 or more beats a minute. The heart of a fit person with a resting rate of 50, beats nine million less each year than an average person’s heart with a resting heart rate of 70,there by reducing the work load of your heart
Aerobic fitness
It gives everyone, the ability to sustain significant activity for a longer period of time. Though it is a necessity for athletes, everyone can follow it as a good health practise.
The American Heart Association recommends that you do exercise that increases your heart rate between 50 and 75% of your maximum heart rate ( maximum heart rate is 220 beats per minute minus your age. For eg.Consider a person of 40 yrs., his maximum heart rate = 180.(220-40) )
So by Involving in an exercise which will raise the heart rates to 50-75% of your maximum heart rate will definitely improve your fitness. However a beginner may not be able to attain this range in the initial phase. During the first few days, do exercise for 10-15 minutes/day. Gradually set the duration as 30-60 minutes/ 4-5 times a week.You should "warm up" and "cool down" for about 5 minutes before and after your exercise. If the exercise is walking or jogging, walk slowly as a warm up. Stretching is an excellent way to warm up and cool down.
links
Excercise for health
Heart rate and excercise
Cardiovascular fitness
Wednesday, April 15, 2009
Essentials of Endocrinology Part ii
NAUSEA:Most common manifestation of thyrotoxicosis is loose stool but occasionally it may be associated with nausea and vomitting.If a patient present with constant nausea and vomitting in the absence of significant structural diseases ,then we can consider the following endocrinal disorders as a differential diagnosis.They are adrenal insufficiency(nausea maximum in the morning associated with vomitting.)and hypercalcaemia.
CONSTIPATION/DIARRHOEA: Hypothyroidism or pan hypopitutarism may present with constipation and abdominal distension. Diarrhoea may occur as a part of autonomic neuropathy involving the gut in diabetes mellitus. Peptic ulceration may occur in zollinger Ellison syndrome.
SKIN CHANGES: In hyperthyroidism the skin is dry and hot, whereas in hypothyroidism skin appears pale sallow or slight yellow and thinning of scalp and lateral eye brow hair. Vitelligo, a common feature of autoimmune hyperthyroiditis and vitamin B12 deficiency. Excessive pigmentation is a feature of Cushing syndrome with increased sebum production causing greasy skin and acne on the face and shoulders. Violaceous cyanosis like skin discoloration may be a feature of carcinoid tumors of gut or lung (because of increased 5 hydroxy indole acetic acid 5HIAA). In hypoadrenalism, there is a pallor with pigmentation of conjunctival membrane beneath the lids, inside the mouth and axilla
MENSES :Regular menstration is a good indication against the androgen excess.,In such cases ,hirsuitism (Excess hair growth) can be considered as constitutional than Pathological.Pathological causes of excess hair growth include polycystic ovarian syndrome,late presentation of congenital adrenal hyperplasia,androgen secreting ovarian tumors.Moreover an increased libido suggests an increased androgen secretion
RENAL STONE: Renal stone may present due to primary hyperparathyroidism or it occur as a part of the syndrome multiple endocrine neoplasia.(MEN Type 1) or else it may run in families as an isolated disorder.
CRAMPS and paraesthesiae:If it is bilateral,it is due to hypoparathyroidism (decreased circulating ionized calcium level) or it may be associated with metabolic/respiratory alkalosis. Refractory cramping after correction of hypocalcaemia due to associated hypomagnesaemia.
Part 1
Source and links
Hutchison's clinical method and endocrineweb
Monday, April 13, 2009
Common method used for the estimation of LDL cholesterol
Friedwald’s Formula:It is the conventional method for the estimation of LDL-cholesterol in fasting specimen
The formula
LDL-cholesterol = Total cholesterol - HDL cholesterol - VLDL
VLDL=TRIGLYCERIDES /5
Limitation of Friedwald's formula
Friedewald formula is unreliable in the presence of chylomicronemia ,hypertriglyceridemia (when plasma triglyceride concentration exceeds 400 mg/dL or 4.52 mmol/L) and in patients with dysbetalipoproteinemia (type III hyperlipoproteinemia).
Further reading
http://www.clinchem.org/cgi/content/full/43/11/2183